National Eye Institute - Eye Disease Prevalence Study Group
The Baltimore Eye Survey, Baltimore, MD: James M. Tielsch, Alfred Sommer, Joanne Katz, Harry A. Quigley

The Barbados Eye Studies, Barbados, West Indies: M. Cristina Leske, Suh-Yuh Wu, Barbara Nemesure, Anselm Hennis, Leslie Hyman, Andrew Schachat
The Beaver Dam Eye Study, Beaver Dam, WI: Barbara E.K. Klein, Ronald Klein, Kristine E. Lee, Scot E. Moss, Sandra C. Tomany

The Blue Mountains Eye Study, Sydney, New South Wales, Australia: Paul Mitchell, Jie Jin Wang, Elena Rochtchina, Wayne Smith, Robert G. Cumming, Karin Attebo, Jai Panchapakesan, Suriya Foran
The Melbourne Visual Impairment Project, Melbourne, Australia: Hugh R. Taylor, Cathy McCarty, Bickol Mukesh, LeAnn M. Weih, Patricia M. Livingston, Mylan Van Newkirk, Cara L. Fu, Peter Dimitrov, Matthew Wensor
Proyecto Vision Evaluation Research, AZ: Sheila K. West, Beatriz Muñoz, Jorge Rodriguez (deceased), Aimee T. Broman, Daniel Finklestein, Robert Snyder
The Rotterdam Eye Study, Rotterdam, the Netherlands: Paulus T.V.M. de Jong, Johannes R. Vingerling, Roger C.W. Wolfs, Caroline C.W. Klaver, Albert Hofman, Redmer van Leeuwen, M. Kamran Ikram, Simone de Voogd
The Salisbury Eye Evaluation Project, Salisbury, MD: Sheila West, Gary Rubin, Karen Bandeen Roche, Beatriz Muñoz, Kathy Turano, Oliver D. Schein, Donald Duncan





• Forme “non visive” > 55 anni 34%
• Forme con conseguenze visive
• 60-70 anni = 12%
• 70-80 anni 35%
• > 90 anni 60%






SMD-FORME CLINICHE
• Predisposizione genetica
• Fase senza alterazioni visive à drusen 

• Fase con riduzione visiva (mono / bilaterale)
A) SECCA
B) UMIDA


SMD incidenza
PATOLOGIE OCULISTICHE
-  MACULOPATIA
Rischio di AMD avanzata in base al numero e al tipo di drusen presenti alla baseline nello studio coorte di Beaver Dam: follow-up a 15 anni